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KMID : 0381920080380020073
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Korean Journal of Microscopy
2008 Volume.38 No. 2 p.73 ~ p.79
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Techniques for Cryo-electron Tomography in Biological Field
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Moon Ji-Young
Han Sung-Sik
Lee Kyung-Eun
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Abstract
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In Biology, Studies Using Electron Microscopy for making Cell Structure to 3D reconstruction very fast development.
Recently, by using Cryo fixation, we can see cell 3D structure without structural change, instead of using chemical
fixation which can change cell structure. Before using this technology, we could understand cell structures only in 2D
images. But now, through cryo-ET, 3D reconstruction of cell structure without artificial structure changes can be possible
and this technology will give us many advantages in Drug delivery and Nanothechnology.
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KEYWORD
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Electron tomography, CEMOVIS, 3D reconstruction
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